Open AccessSemen cryopreservation as an oncofertility treatment in 122 Japanese men with cancer: A decade‐long study
Author(s) -
Kobayashi Hideyuki,
Tamura Koji,
Tai Toshihiro,
Nagao Koichi,
Nakajima Koichi
Publication year - 2017
Publication title -
reproductive medicine and biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.005
H-Index - 22
eISSN - 1447-0578
pISSN - 1445-5781
DOI - 10.1002/rmb2.12044
Subject(s) - semen , sperm bank , oncofertility , sperm , fertility preservation , semen cryopreservation , cryopreservation , fertility , medicine , reproductive medicine , semen analysis , testicular cancer , cancer , gynecology , andrology , sperm motility , subspecialty , biology , infertility , pregnancy , population , family medicine , embryo , genetics , environmental health , microbiology and biotechnology
Purpose Oncofertility is a subspecialty that is concerned with helping patients with cancer preserve their ability to have children in the future. For men, sperm banking is an established way to preserve fertility. The aim was to determine the prefreeze semen characteristics and reproductive outcomes according to cancer type for men who chose semen cryopreservation. Methods The records of 122 men with cancer who requested semen cryopreservation at the authors' hospital from 2006 to 2015 were reviewed. The mean patient age when the semen was cryopreserved was 33.6 years. Results The 122 men who banked sperm during the study period had the following types of cancer: testicular (44.3%), hematological (31.1%), digestive (8.2%), and other types (16.4%). The mean sperm concentration by cancer type was 30.5 × 10 6 /mL for testicular, 45.0 × 10 6 /mL for hematological, 40.5 × 10 6 /mL for digestive, and 68.4 × 10 6 /mL for the other types. The mean sperm motility by cancer type was 59.6% for testicular, 50.1% for hematological, 43.0% for digestive, and 44.8% for the other types. For 12 (9.8%) men who used the banked semen, there were five (41.7%) clinical pregnancies. Conclusion Semen cryopreservation is a simple procedure that can be accomplished quickly and can preserve fertility.