Open AccessB urkholderia pseudomallei in cystic fibrosis and treatment complications
Author(s) -
Radhakrishghmeh,
Morton Judith
Publication year - 2015
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.86
Subject(s) - burkholderia pseudomallei , cystic fibrosis , melioidosis , medicine , sputum , clearance , antibiotics , adverse effect , sputum culture , pathogen , intravenous antibiotics , immunology , microbiology and biotechnology , pathology , bacteria , biology , tuberculosis , genetics , urology
Abstract A healthy 29‐year‐old A ustralian man with cystic fibrosis ( CF ) grew B urkholderia pseudomallei on a routine sputum culture 1 month after returning from holiday in T hailand. He underwent a 12‐month treatment regime with multiple antibiotics resulting in a number of adverse events. Sputum cultures were cleared of the pathogen and remain negative 8 years post‐treatment. There were no clinical sequelae and no deterioration in lung function. Few reports have been published to date on melioidosis in CF patients. The proposed management for this infection includes multiple antibiotics regimens for prolonged periods of time, which may result in adverse events. Optimal treatment and length of treatment are currently determined on an individual basis.