Open AccessEndobronchial cryptococcosis induced by C ryptococcus gattii mimicking metastatic lung cancer
Author(s) -
Nakashima Kazuhisa,
Akamatsu Hiroaki,
Endo Masahiro,
Kawamura Ichiro,
Nakajima Takashi,
Takahashi Toshiaki
Publication year - 2014
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.64
Subject(s) - medicine , cryptococcus gattii , left main bronchus , mediastinal lymphadenopathy , cryptococcosis , bronchoscopy , lung cancer , radiology , lung , biopsy , left lung , pathology
A 41‐year‐old previously healthy J apanese man complained of cough for 2 months. A chest computed tomography scan revealed a mass in his left lung with multiple mediastinal lymphadenopathy. Brain magnetic resonance imaging showed many small, enhancing lesions. He was admitted to our hospital for further evaluation of an abnormal shadow suspicious for metastatic lung cancer. Bronchoscopy showed aggregated white nodes in the compressively stenosed left main bronchus. A specimen from transbronchial biopsy showed many foamy and yeast‐like cells. Cultures and additional gene analysis identified these cells as C ryptococcus gattii . Antifungal treatment was commenced and his symptoms clearly improved. To our knowledge, this is the first case of an aggressive form of endobronchial cryptococcosis caused by C . gattii .