Open AccessEndobronchial T ‐cell lymphoma in a patient with chronic pyothorax
Author(s) -
Matsumoto Shinsaku,
Fujimoto Nobukazu,
Fuchimoto Yasuko,
Asano Michiko,
Yano Tomofumi,
Kishimoto Takumi
Publication year - 2015
Publication title -
respirology case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 9
ISSN - 2051-3380
DOI - 10.1002/rcr2.103
Subject(s) - medicine , bronchoscopy , cd5 , bronchus , cd20 , pathology , lymphoma , differential diagnosis , pathological , biopsy , right main bronchus , peripheral t cell lymphoma , radiology , lung , respiratory disease , t cell , immune system , immunology
We report a very rare case of primary endobronchial peripheral T ‐cell lymphoma ( PTCL ) not otherwise specified ( NOS ), which presented as an endobronchial tumor obstructing the main airway. An 81‐year‐old man was referred to our hospital for a 1‐month history of productive cough and wheeze. Computed tomography revealed chronic pyothorax with calcified foci in the right lung and a mass inside the bronchus intermedius. Flexible bronchoscopy identified an endobronchial tumor obstructing the bronchus intermedius. The biopsy specimen showed an infiltration composed predominantly of small atypical lymphocytes. Immunohistochemical analyses demonstrated that the proliferating cells were positive for CD 3, CD 4, and CD 5 and negative for CD 8 and CD 20. Pathological tests confirmed that the case was PTCL ‐ NOS . PTCL ‐ NOS should be considered in the differential diagnosis of endobronchial tumors.