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Infectious diseases continue to threaten the lives of young children in low and middle-income countries (LMICs). Pediatric assessment of anti-infectives for these children should be initiated early. This assessment can center around an iterative dose-selection process that is informed by an integrated prediction platform based on physiologically-based pharmacokinetic and pharmacodynamic (PBPK-PD) models. This article is protected by copyright. All rights reserved.

Model‐Informed Assessment of Anti‐Infectives for Young Children in Low‐ and Middle‐Income Countries