Open AccessToxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
Author(s) -
Luo Lijuan,
Shen Nan,
Chen Wenjuan,
Luo Chengjuan,
Huang Xiaohang,
Jiang Yuelian,
Cao Qing
Publication year - 2021
Publication title -
pediatric investigation
Language(s) - English
Resource type - Journals
ISSN - 2574-2272
DOI - 10.1002/ped4.12290
Subject(s) - toxoplasmosis , toxoplasma gondii , hematopoietic stem cell transplantation , medicine , transplantation , complication , bone marrow transplant , bone marrow transplantation , pediatrics , bone marrow , immunology , intensive care medicine , surgery , antibody
Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. Case presentation We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next‐generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed. Conclusion Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre‐transplant screening and post‐transplant monitoring and prevention in future according to the national conditions of our country.