Open AccessFirst Isolation and Structure Elucidation of GDNT‐β‐Glu – Tetraether Lipid Fragment from Archaeal Sulfolobus Strains
Author(s) -
Scholte Alexander,
Hübner Christoph,
Ströhl Dieter,
Scheufler Olaf,
Czich Steffen,
Börke Julia M.,
Hildebrand Gerhard,
Liefeith Klaus
Publication year - 2021
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.202100154
Subject(s) - sulfolobus acidocaldarius , sulfolobus solfataricus , sulfolobus , archaea , chemistry , stereochemistry , lipid ii , biochemistry , enzyme , biosynthesis , gene
Abstract Due to their special chemical structure, tetraether lipids (TEL) represent essential elements of archaeal membranes, providing these organisms with extraordinary properties. Here we describe the characterization of a newly isolated structural element of the main lipids. The TEL fragment GDNT‐β‐Glu was isolated from Sulfolobus metallicus and characterized in terms of its chemical structure by NMR‐ and MS‐investigations. The obtained data are dissimilar to analogically derived established structures – in essence, the binding relationships in the polar head group are re‐determined and verified. With this work, we provide an important contribution to the structure elucidation of intact TEL also contained in other Sulfolobus strains such as Solfulobus acidocaldarius and Sulfolobus solfataricus .