Open AccessDiabetes Treatment: Selective Synthetic Receptor for Glucose
Author(s) -
Shirinfar Bahareh,
Ahmed Nisar
Publication year - 2019
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.201800279
Subject(s) - binding affinities , receptor , urea , chemistry , affinities , combinatorial chemistry , diabetes mellitus , computational biology , biochemistry , nanotechnology , medicine , biology , endocrinology , materials science
A new synthetic receptor has selective and strong interactions with glucose, directing towards future diabetes management. These studies pave the way to design future selective receptors that can potentially be modified with combinations of urea walls having multiple H‐binding sites to generate hydrophilic affinities, and the incorporation of promising aromatic systems for hydrophobic π‐interactions with glucose CH.