Open AccessNew Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis
Author(s) -
Oliveri Valentina
Publication year - 2015
Publication title -
chemistryopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 29
ISSN - 2191-1363
DOI - 10.1002/open.201500155
Subject(s) - biomedicine , cancer , oxidative stress , neuroscience , glycoconjugate , nanotechnology , medicine , disease , chemistry , pharmacology , bioinformatics , biochemistry , biology , materials science , pathology
Metal dyshomeostasis is involved in several pathologies, making metal ions promising therapeutic targets. Conjugating 8‐hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility, selectivity, and multifunctionality. Biological evaluation of these compounds suggests they have potential as therapeutic agents in diseases related to metal dyshomeostasis.