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A new method for absolute quantitation MRS metabolites
Author(s) -
Barantin Laurent,
Pape Alain Le,
Akoka Serge
Publication year - 1997
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910380203
Subject(s) - absolute (philosophy) , chemistry , nuclear magnetic resonance , chromatography , physics , philosophy , epistemology
Abstract A new method for absolute of MRS spectra is presented. This method is not based on a reference peak, derived from a real NMR signal, but rather on a synthesized NMR reference produced by an electronic device, transmitted by a broad‐band antenna to avoid quality factor variations. This signal is therefore received at the same time as the sample signal. The reference line produced is stable in time (maximum variation lower than 2%) and allows precise and accurate measurement of absolute concentrations (mean error lower than 3%) in vitro and in vivo .