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Triplet NOAH supersequences optimised for small molecule structure characterisation
Author(s) -
Claridge Tim D.W.,
Mayzel Maksim,
Kupče Ēriks
Publication year - 2019
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.4887
Subject(s) - homonuclear molecule , chemistry , heteronuclear single quantum coherence spectroscopy , molecule , series (stratigraphy) , sampling (signal processing) , two dimensional nuclear magnetic resonance spectroscopy , small molecule , computational chemistry , chemical physics , molecular physics , nuclear magnetic resonance , stereochemistry , organic chemistry , detector , physics , optics , paleontology , biochemistry , biology
Abstract A series of NMR supersequences are presented for the time‐efficient structure characterisation of small molecules in the solution state. These triplet sequences provide HMBC, HSQC, and one homonuclear correlation experiment of choice according to the NMR by Ordered Acquisition using 1 H detection principle. The experiments are demonstrated to be compatible with non‐uniform sampling schemes and may be acquired and processed under full automation.