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Oncological outcomes of CO 2 laser cordectomies for glottic squamous cell carcinoma with respect to anterior commissure involvement and margin status
Author(s) -
OsuchWójcikiewicz Ewa,
Rzepakowska Anna,
Sobol Maria,
Bruzgielewicz Antoni,
Niemczyk Kazimierz
Publication year - 2019
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.23130
Subject(s) - cordectomy , anterior commissure , medicine , basal cell , surgery , surgical margin , retrospective cohort study , resection , larynx , laryngeal neoplasm
Background and Objectives Controversial prognostic factors of primary CO 2 laser cordectomy are anterior commissure involvement (ACI) and status of margin. Study Design/Materials and Methods Retrospective analysis of oncological outcomes in 102 patients with early glottic cancer undergoing laser cordectomy between 2013 and 2015. Results The T stages distribution included: 72.6% T1a, 14.7% T1b, and 12.7% T2. The ACI was diagnosed in 26 patients. The primary cordectomy was radical in 72 patients. The 2‐ and 5‐year disease free survival (DFS) for all patients were, respectively, 83.3% and 77.3%.The 2‐year DFS rates for T1a, T1b, T2 were, respectively, 91.7%, 66.7%, and 53.9% and the differences were statistically significant ( P < 0.001). The 2‐year DFS rates according to the ACI and free anterior commissure tumors were, respectively, 65.4% and 89.2%, and the ACI indicated worse prognosis ( P = 0.057). The 2‐year DFS rates according to margins status were higher for patients with close or positive margins, who had second resection (88.9%) compared with those of negative margins (80.9%) ( P = 0.340). Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.