Open AccessNot just another nasal polyp: Chondro‐osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract
Author(s) -
Yu Yue,
Tan Chien Sheng,
Koh Leslie Timothy
Publication year - 2021
Publication title -
laryngoscope investigative otolaryngology
Language(s) - English
Resource type - Journals
ISSN - 2378-8038
DOI - 10.1002/lio2.580
Subject(s) - nasal cavity , medicine , hamartoma , pathology , nose , respiratory tract , anatomy , respiratory system
Objectives Chondro‐osseous respiratory epithelial adenomatoid hamartomas (COREAH) are extremely rare benign lesions in the sinonasal cavity. We aim to (a) report two cases of COREAH and (b) perform a literature review with a summary on previously published cases of COREAH till August 2019. Methods A literature review identified 16 cases, but only 12 cases from publications from 2005 to 2019 were included in analysis. In addition, we report two cases of COREAH from our tertiary academic medical center. Results COREAH is found in patients from 3 to 83 years old. It originates from various sites in the nasal cavity and sinuses but the most common location is the lateral nasal wall. Calcification on imaging is a common finding. Conclusion COREAH is an uncommon entity that is important to recognize and distinguish from other sinister nasal masses. It is a slow growing benign lesion which lacks aggressive features on imaging. Future studies are needed to evaluate the possibility of an underlying genetic predisposition. Level of Evidence 4.