Assessment of the selectivity equivalence of DB‐608 and DB‐624 open‐tubular columns for gas chromatography

The solvation parameter model is used to characterize the selectivity of DB‐608 and DB‐624 open‐tubular columns at five equally spaced temperatures over the range 60 to 140°C. The system constants for the DB‐608 and DB‐624 columns were used as selectivity parameters to search a database of open‐tubular columns to identify columns with similar selectivity. The search was refined using the absolute deviation of the system constants and retention factor regression models for varied compounds. For method development it is shown that the selectivity of the poly(cyanopropylphenyldimethylsiloxane) stationary phase containing 6% cyanopropylphenylsiloxane monomer (DB‐1301) is equivalent to DB‐624 and the poly(dimethyldiphenylsiloxane) stationary phases containing either 50 or 65% diphenylsiloxane monomer (Rtx‐50 and Rtx‐65) are suitable choices for DB‐608.