Premium
Allgemeine Kontrolle der Aminosäurebiosynthese in Mutanten von Candida spec. EH 15/D
Author(s) -
Bode R.,
Casper P.
Publication year - 1983
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19830230703
Subject(s) - asparagine , derepression , auxotrophy , histidine , methionine , amino acid , threonine , biochemistry , arginine , homoserine , chemistry , amino acid synthesis , serine , aspartic acid , mutant , biology , lysine , enzyme , gene , psychological repression , quorum sensing , gene expression , virulence
The general control of amino acid biosynthesis was investigated in Candida spec. EH 15/D, using single and double mutant auxotrophic strains and prototrophic revertants starved for their required amino acids. These experiments show that starvation for lysine, histidine, arginine, leucine, threonine, proline, serine, methionine, homoserine, asparagine, glutamic acid or aspartic acid can result in derepression of enzymes. A correlation was found between the degree of derepression, growth of strains, and concentration of required amino acids. The amino acids pcol pattern of mutants and revertants is different from that in the wild type strain.