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Physiologie und Biochemie der Streptomyceten. III. Einbau von D ‐Glucose‐u‐ 14 C in Paromomycin als Indikator für die Antibioticabildung durch Streptomyces albus var. metamycinus nov. var.
Author(s) -
Köster H.,
Liebermann B.,
Reuter G.
Publication year - 1975
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19750150607
Subject(s) - paromomycin , streptomyces albus , biosynthesis , metabolism , chemistry , biology , botany , biochemistry , streptomyces , antibiotics , bacteria , aminoglycoside , enzyme , genetics
Paromomycin was isolated from culture filtrates of Streptomyces albus var. metamycinus nov. var. after feeding the growing cultures with D‐glucose‐u‐ 14 C. From the different incorporation rates conclusions concerning different features of the paromomycin biosynthesis (utilization of the carbon source, proportional and disproportional changes of the rates of synthesis) could be drawn. Uptake and metabolism of glucose are discussed.