Open AccessCorrelation of the peak oxygen consumption and ventilatory aerobic threshold by cardiopulmonary exercise testing with atrial fibrillation recurrences after ablation in patients with paroxysmal atrial fibrillation
Author(s) -
Yamashita Daiki,
Kamikawa Shigeshi,
Tanaka Ryou,
Tabita Natsumi,
Nishimura Saori,
Mitsuoka Miyuki,
Higashiya Shunich,
Yamaji Hirosuke,
Murakami Takashi,
Hina Kazuyoshi,
Kusachi Shozo
Publication year - 2020
Publication title -
journal of arrhythmia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 21
eISSN - 1883-2148
pISSN - 1880-4276
DOI - 10.1002/joa3.12350
Subject(s) - medicine , cardiology , atrial fibrillation , anaerobic exercise , ablation , vo2 max , receiver operating characteristic , anesthesia , heart rate , blood pressure , physical therapy
Background The cardiopulmonary function is hypothesized to be associated with atrial fibrillation/atrial tachyarrhythmia (AF/AT) recurrence after AF ablation. Purpose To clarify the relationship between the cardiopulmonary function after successful ablation and AF/AT recurrence. Methods We examined 31 patients with paroxysmal AF who underwent AF ablation. Cardiopulmonary exercise testing (CPET) was performed at 1month after the ablation. A continuously increasing loading method on a bicycle ergometer was employed for the CPET. Results No adverse events, including AF/AT recurrence, occurred during the CPET. Among 31 patients, AT/AF recurrence was observed in seven (23%). The ventilatory anaerobic threshold (VAT) and peak oxygen consumption (VO2) were significantly higher in patients without AF/AT recurrence than in those with AT/AF recurrences (peak VO2 23.6 ± 5.7 vs 17.2 ± 4.1 mL/kg/min; VAT, 16.7 ± 2.8 vs 13.8 ± 2.7 mL/min/kg). The areas under the receiver operating characteristic curve for the peak VO2 and VAT were 0.786 ( P < .01) and 0.789( P < .01), respectively. Both indices had a sensitivity of 70%–80% and specificity of 70%–80% for predicting AT/AF recurrence. Similar results were obtained for the percent values of the predicted peak VO2 and VAT. Conclusions The present pilot study found that CPET can be performed safely at approximately 1 month after AF ablation. The peak VO2 and VAT were significantly associated with AT/AF recurrence. The peak VO2 and VAT were thought to provide helpful information regarding AT/AF recurrence.