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An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019
Author(s) -
Toovey Oliver T. R.,
Kulkarni Priti,
David Joicy,
Patel Ayushi,
Lai Florence Y.,
Burns Joyce,
Thompson Catherine,
Ellis Joanna,
Tang Julian W.
Publication year - 2021
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.26647
Subject(s) - outbreak , keratoconjunctivitis , virology , keratitis , biology , medicine , genetics
We report a large epidemic ( n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye disease being present, these were not significantly different between the different AdV species, with similar rates of pseudomembrane formation and keratitis observed in patients with AdV species B as for those with AdV species D.