English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Significant changes in the shape, size and position of the bladder during radiotherapy ( RT ) treatment for bladder cancer have been correlated with high local failure rates; typically due to geographical misses. To account for this, large margins are added around the target volumes in conventional  RT ; however, this increases the volume of healthy tissue irradiation. The availability of cone beam computed tomography ( CBCT ) has not only allowed in‐room volumetric imaging of the bladder, but also the development of adaptive radiotherapy ( ART ) for modification of plans to patient‐specific changes. The aim of this review is to: (1) identify and explain the different  ART  techniques being used in clinical practice and (2) compare and contrast these different  ART  techniques to conventional  RT  in terms of target coverage and dose to healthy tissue: A literature search was conducted using  EMBASE ,  MEDLINE  and Scopus with the key words ‘bladder, adaptive, radiotherapy/radiation therapy’. 11 studies were obtained that compared different adaptive  RT  techniques to conventional  RT  in terms of target volume coverage and healthy tissue sparing. All studies showed superior target volume coverage and/or healthy tissue sparing in adaptive  RT  compared to conventional  RT . Cross‐study comparison between different adaptive techniques could not be made due to the difference in protocols used in different studies. However, one study found daily re‐optimisation of plans to be superior to plan of the day technique. The use of adaptive  RT  for bladder cancer is promising. Further study is required to assess adaptive  RT  versus conventional  RT  in terms of local control and long‐term toxicity.

Adaptive radiation therapy for bladder cancer: a review of adaptive techniques used in clinical practice