Premium
Synthesis and characterization of 2‐hydroxymethyl‐1‐methyl‐4‐nitro‐5‐imidazolcarbonitrile‐4, 5‐ 14 C
Author(s) -
Ellsworth Robert L.,
Meriwether Henry T.,
Mertel Holly E.
Publication year - 1990
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580280702
Subject(s) - chemistry , oxalic acid , yield (engineering) , nitro , hydroxymethyl , combinatorial chemistry , stereochemistry , organic chemistry , alkyl , materials science , metallurgy
Preparation of the title compound, a key intermediate required to assist in the investigation and development of a new class of substances for controlling coccidiosis, is described. This labeled substance was synthesized in 10 steps, with a 17% overall radiochemical yield, from oxalic‐1,2‐ 14 C acid.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom