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Syntheses of carbon‐13 and carbon‐14 labeled (methylenecyclopropyl)acetyl‐CoA
Author(s) -
Baldwin John E.,
Widdison Wayne C.
Publication year - 1990
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580280207
Subject(s) - chemistry , acetic acid , carbon 14 , ethanol , acetyl coa , carbon fibers , coenzyme a , stereochemistry , organic chemistry , enzyme , physics , composite number , materials science , composite material , quantum mechanics , reductase
Methylenecyclopropyllithium reacts with 13 C‐ or 14 C‐oxirane to give labeled 2‐(methylenecyclopropyl)ethanol, which may be converted in three steps to the corresponding coenzyme A thioesters of (methylenecyclopropyl)acetic acid.
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