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The synthesis of deuterium labelled mono‐hydroxy metabolites of phenytoin
Author(s) -
Hoskins John A
Publication year - 1984
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580210709
Subject(s) - chemistry , phenytoin , deuterium , metabolite , stereochemistry , biochemistry , epilepsy , physics , quantum mechanics , neuroscience , biology
The synthesis of the 3‐hydroxyphenyl and 4‐hydroxyphenyl metabolites of 5,5‐diphenylhydantoin (Phenytoin) labelled with deuterium in either of the two phenyl rings and 5(4‐hydroxy‐[ 2 H 4 ]phenyl)‐5‐[ 2 H 5 ] phenylhydantion is described.