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Labelled compounds of interest as antitumour agents I: N‐methylformamide and N, N‐dimethylformamide
Author(s) -
Threadgill Michael D,
Gate E Nicholas
Publication year - 1983
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580200403
Subject(s) - chemistry , formamide , dimethylformamide , methyl group , deuterium , medicinal chemistry , group (periodic table) , stereochemistry , organic chemistry , physics , quantum mechanics , solvent
Efficient preparations of N‐methylformamide (an active antitumour agent) have been developed in which the compound is labelled with 14 C in the formyl group, with 14 C in the methyl group and with deuterium in the methyl group. N, N‐Dimethyl‐ 14 C‐formamide has also been synthesised.