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The preparation of 7‐chloro‐5‐(2‐chlorophenyl)‐1,3‐dihydro‐2H‐1,4‐benzodiazepin‐2‐one‐5‐ 14 C
Author(s) -
Kaegi H. H.,
Burger W.
Publication year - 1982
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580190811
Subject(s) - chemistry , yield (engineering) , diazepine , barium carbonate , carbon 14 , ring (chemistry) , carbonate , barium , carbon fibers , medicinal chemistry , radiochemistry , nuclear chemistry , combinatorial chemistry , stereochemistry , organic chemistry , raw material , materials science , physics , quantum mechanics , composite number , metallurgy , composite material
7‐Chloro‐5‐(2‐chlorophenyl)‐1,3‐dihydro‐2H‐1,4‐benzodiazepin‐2‐one labeled with carbon‐14 in carbon 5 of the diazepine ring has been synthesized. The compound was prepared in a multistep synthesis from barium carbonate‐ 14 C in an overall yield of 23%.