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Synthesis of pethidine derivatives : 14 C labelled DL‐phenoperidine
Author(s) -
Duc C. Luu,
Charlon Cl.,
Delord Cl. Agnius,
Cros J.,
Monsarrat B.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580150182
Subject(s) - chemistry , diethanolamine , pethidine , hydrochloride , cyanide , chloride , organic chemistry , medicinal chemistry , pharmacology , analgesic , medicine
The phenoperidine hydrochloride was labelled with 14 C at the carboethoxy group, in six steps from diethanolamine. The carbon‐14 labelled benzyl cyanide precursor was prepared from Na 14 CN and benzyl chloride.