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Preparation of carbon‐14 labeled 2‐phenyl‐3‐[ p ‐(2‐diethylaminoethoxy) phenyl]‐6‐methoxyindene hydrochloride
Author(s) -
Thomas Richard C.,
Marlatt Paul E.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580140604
Subject(s) - chemistry , hydrochloride , yield (engineering) , phenylacetic acid , medicinal chemistry , sequence (biology) , stereochemistry , organic chemistry , biochemistry , materials science , metallurgy
2‐Phenyl‐3‐[ p ‐(2‐diethylaminoethoxy)phenyl]‐6‐methoxyindene‐3 14 C hydrochloride was prepared from phenylacetic acid‐1‐ 14 C in a four step sequence of reactions. The final product was obtained in 12.5% yield at a specific activity of 0.79 mCi per mM.