Premium
L‐carboranylalanine substituted TMV, a highly boron labeled virus as a model for slow neutron therapy of tumors
Author(s) -
Escher E.,
Leukart O.,
Kriwaczek V. M.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580140403
Subject(s) - decaborane , chemistry , tobacco mosaic virus , boron , neutron capture , virus , virology , combinatorial chemistry , radiochemistry , organic chemistry , medicine
The use of the newly synthesized 10‐boron atoms containing amino acid L ‐o‐carboranylalanine (Car) as a useful tool in slow neutron therapy of tumors is proposed and its attempted application with a Car‐substituted Tobacco mosaic virus (TMV) is described and discussed. Also the synthesis of 10 B‐enriched decaborane as a precursor of Car is described.