Premium
Synthesis of Methyl Derivatives of 4 H ‐Furo[2,3‐ h ]quinolin‐4‐one and 5 H ‐Furo[3,2‐ g ]quinolin‐5‐one
Author(s) -
Rao Vadapalli S.,
Rodighiero Paolo,
Chilin Adriana,
Castellin Andrea,
Manzini Paolo,
Guiotto Adriano
Publication year - 1997
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199719970221
Subject(s) - chemistry , yield (engineering) , stereochemistry , medicinal chemistry , computational chemistry , thermodynamics , physics
Abstract Synthesis of the linear and angular furoquinolin‐4‐one derivatives 6 and 12 was performed, using nitrobenzofurans 3 and 9 as key intermediates. These compounds were reduced to the corresponding aminobenzofurans 4 and 10 , which were condensed in two steps to yield, the linear furoquinolin‐4‐ones 6a,b and the angular ones 12a,b .