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Absolute Configuration of 1,2,3,4‐Tetrahydro‐4‐hydroxyisoquinolines
Author(s) -
Snatzke Günther,
Meese Claus O.
Publication year - 1987
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198719870115
Subject(s) - absolute configuration , chemistry , debrisoquine , absolute (philosophy) , resolution (logic) , metabolite , stereochemistry , artificial intelligence , biochemistry , computer science , metabolism , philosophy , cyp2d6 , epistemology , cytochrome p450
Preparation, optical resolution, and absolute configuration of some 1,2,3,4‐tetrahydro‐4‐hydroxyisoquinolines, including the major human metabolite of debrisoquine (4‐hydroxydebrisoquine, 2 ), are described.