Synthesis and spectral properties of 5‐methylthio‐4 H ‐1‐( p ‐substituted‐phenyl)‐3a‐( p ‐substituted‐phenyl)‐9‐[( m ‐; and p ‐substituted)‐phenoxy]‐3a,4‐dihydro[1,2,4]oxadiazolo[4,5‐ a ][1,5]benzodiazepines

The preparation of eight novel substituted [1,2,4]oxadiazolo[4,5‐ a ][1,5]benzodiazepines which have potentially useful pharmacological properties; by 1,3‐cycloaddition of benzonitrile oxides, generated in situ from benzohydroxamoyl chloride and triethylamine, to 1,5‐benzodiazepine derivatives is described. The structure of all products was corroborated by ir, 1 H‐nmr, 13 C‐nmr and ms.