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A carbon‐13 Nmr assignment study of 3,5‐diarylisoxazoles
Author(s) -
Baumstark Alfons L.,
Chrisope Douglas R.,
Keel Rebecca A.,
Boykin David W.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170815
Subject(s) - chemistry , isoxazole , aryl , ring (chemistry) , carbon 13 nmr , chemical shift , fluorine 19 nmr , carbon fibers , fluorine , computational chemistry , nuclear magnetic resonance spectroscopy , medicinal chemistry , organic chemistry , alkyl , materials science , composite number , composite material
Abstract The assignment of the carbon‐13 nmr resonances of 3‐(aryl)‐5‐phenylisoxazoles (I) and 3‐phenyl‐5‐(aryl)‐isoxazoles (II) in dimethylsulfoxide‐ d 6 has been made. The assignments were made by using model compounds, chemical shift arguments, coupling with fluorine substituents, and shifts resulting from quaternization of the isoxazole ring. A carbon‐13 nmr method for distinguishing between I and II which can be produced simultaneously by certain synthetic methods is presented.