Open AccessPrimary hepatic lymphoma: A rare case report
Author(s) -
Mehta Nishkarsh,
Jayapal Loganathan,
Goneppanavar Mangala,
Nelamangala Ramakrishnaiah Vishnu Prasad
Publication year - 2019
Publication title -
jgh open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 8
ISSN - 2397-9070
DOI - 10.1002/jgh3.12131
Subject(s) - medicine , vincristine , lymphoma , prednisone , biopsy , liver biopsy , radiology , abdominal pain , differential diagnosis , rituximab , vomiting , surgery , chemotherapy , cyclophosphamide , pathology
Primary hepatic lymphoma (PHL) is a rare clinical entity comprising 0.016% of all cases of non‐Hodgkin's lymphoma and 0.4% of extranodal non‐Hodgkin's lymphoma and can be missed easily. Here, we report a case of PHL treated with primary hepatic resection followed by an Rituximab Cyclophosphamide Doxorubicin Vincristine Prednisone (R‐CHOP) chemotherapy regimen, diagnosed after postoperative biopsy report. The patient presented with complaints of pain abdomen, vomiting, anorexia, and weight loss. She had hepatomegaly and no other significant finding. Blood investigations were unremarkable. Biopsy or fine needle aspiration cytology (FNAC) was not taken before surgery. Contrast‐enhanced computed tomography of the abdomen demonstrated well‐defined solid mass with central hypodense fluid attenuating area in the liver with a thin pseudocapsule. The differential diagnoses considered were secondary to the liver, hepatocellular carcinoma, and hemangioma. Left hepatectomy with the removal of the middle hepatic vein was performed. The postoperative biopsy was reported as diffuse large B cell lymphoma of the liver.