Open AccessSignificance of ileal and/or cecal wall thickening on abdominal computed tomography in a tropical country
Author(s) -
Kumar Amit,
Rana Surinder S,
Nada Ritambhra,
Kalra Naveen,
Sharma Ravi K,
Dutta Usha,
Gupta Rajesh
Publication year - 2019
Publication title -
jgh open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 8
ISSN - 2397-9070
DOI - 10.1002/jgh3.12103
Subject(s) - cecum , medicine , colonoscopy , ileocecal valve , ascending colon , ileum , crohn's disease , histopathology , gastroenterology , asymptomatic , radiology , abdominal pain , pathology , colorectal cancer , disease , cancer
Background and Aim Clinical significance of ileocecal thickening on computed tomography (CT) is uncertain. We conducted this prospective study to determine the clinical relevance of ileal and/or cecal thickening on CT. Methods All patients with ileocecal thickening on CT were prospectively evaluated with ileocolonoscopy, biopsy, and other relevant investigations. Results Fifty patients (29 males, mean age 36.8 ± 13.21 years) were studied. Thirty nine (78%) patients presented with abdominal pain. On CT, 46 (92%) had a thickened wall of terminal ileum, 25 (50%) cecum, and 21 (42%) of both cecum and ileum. The mean wall thickness of ileum and cecum on CT was 7.23 + 3.2 mm and 5.5 + 3.1 mm, respectively. Final diagnosis was tuberculosis in 24 (48%) patients, Crohn's disease (CD) in 10 (20%), and adenocarcinoma in 1 patient. Colonoscopy demonstrated abnormal findings in 41 patients (82% patients with mucosal ulcerations being most common ( n = 20 (40%). Of 15 (30%) patients with ileocecal bowel wall thickening, 4 (8%) patients had normal colonoscopy and histopathology (incidental ileocecal wall thickening), and in the remaining 11 patients, histopathology showed non‐specific findings and these patients were asymptomatic without any specific treatment on last follow up ranging from 3 to 24 months. Involvement of cecum with ileocecal junction, ascending colon involvement, peri‐ileocecal stranding, and long‐segment stricture was significantly more common in patients with underlying disease as compared to nondiseased patients ( P < 0.05). Conclusion A majority of patients with ileocecal wall thickening on CT have an underlying disease and should be further investigated by ileocolonoscopy and biopsy.