Open AccessConcern regarding quality and quality of muscle
Author(s) -
Saitoh Masakazu,
Ishida Junichi,
Konishi Masaaki,
Springer Jochen
Publication year - 2015
Publication title -
journal of cachexia, sarcopenia and muscle
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.803
H-Index - 66
eISSN - 2190-6009
pISSN - 2190-5991
DOI - 10.1002/jcsm.12081
Subject(s) - myoglobin , medicine , creatinine , colorectal cancer , wasting , anaerobic exercise , cachexia , muscle mass , cancer cachexia , cancer , gastroenterology , oncology , urology , physical therapy , biochemistry , biology
Creatinine and myoglobin are poor predictors of anaerobic threshold in colorectal cancer and health. It certainly has been agreed upon that lean muscle mass (LMM) is essential in predicting aerobic performance of healthy and non-disseminated colorectal cancer (CRC) patients. It was confirmed that LMM is a powerful predictor of aerobic performance and mortality.1,2 Additionally, there are some reports that creatinine and myoglobin were surrogates for muscle mass.3,4 We believed this is a very important study and congratulate the authors for their innovative study. However, anaerobic threshold was significantly lower in the CRC patients compared with healthy controls, although there was no significant difference in serum creatinine, myoglobin, and LMM in this study. There is no significant correlation between serum creatinine or myoglobin and aerobic performance. I would like to address three issues to understanding of findings this study.