Open AccessThe study of biochemical profile of cyst fluid and diffusion‐weighted magnetic resonance imaging in differentiating hepatic hydatid cysts from liver simple cysts
Author(s) -
Shanshan Wang,
Hui Li,
Yan Liu,
Li Wang,
Yongfang Ren,
Yan Wang,
Kader Muhetarjiang,
Wenxiao Jia
Publication year - 2018
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/jcla.22192
Subject(s) - cyst , magnetic resonance imaging , hydatid cyst , medicine , echinococcosis , differential diagnosis , cystic echinococcosis , pathology , nuclear medicine , radiology
Purpose The aim of this study was to investigate the value of biochemical profile of cyst fluid and diffusion‐weighted imaging ( DWI ) in differentiating hepatic hydatid cysts ( HC s) from liver simple cysts. Materials and methods Forty‐six patients underwent MR imaging. Twenty‐nine patients had 29 hydatid cysts and 17 patients had liver simple cysts. Thirteen patients with hydatid cysts and seven patients with liver simple cysts were evaluated with cyst fluid biochemical analysis. The concentration of glucose, protein, calcium ion (Ca 2+ ) electrolyte, macroscopic appearance, and parasitological sediment were evaluated in this study. Results In the respect of biochemical analysis cyst fluid, the concentration of glucose and calcium ion of HC s was significantly higher than that of the liver simple cysts. In the respect of DWI , in the b 1000 s/mm 2 value in respect of mean application data center (ADC) values, there was a statistically significant difference between HC s group (the mean value was (2.50±0.79)×10 −3 mm/s 2 ) and liver simple cysts group (the mean value was (2.92±0.66)×10 −3 mm/s 2 ). However, no statistically significant results were obtained in the ADC measurements of b 500 s/mm 2 between two groups. Conclusion The analysis of cyst fluid combined with the measurement of ADC values in the b 1000 s/mm 2 value could be considered a promising parameter as an alternative to the differential diagnosis of hepatic hydatid cysts from liver simple cysts.