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Case of inverted papillary urothelial carcinoma in the ureter
Author(s) -
Nirei Takuma,
Nakaigawa Noboru,
Matsumura Mai,
Kataoka Toshiaki,
Nagasaka Takahiro,
Aomori Kota,
Ito Yusuke,
Muraoka Kentaro,
Yao Masahiro
Publication year - 2022
Publication title -
iju case reports
Language(s) - English
Resource type - Journals
ISSN - 2577-171X
DOI - 10.1002/iju5.12403
Subject(s) - ureter , medicine , papillary tumor , urothelial carcinoma , ureteroscopy , ureteral neoplasm , urology , inverted papilloma , magnetic resonance imaging , carcinoma , radiology , pathology , cancer , transitional cell carcinoma , papilloma , bladder cancer
Urothelial neoplasms with a varus growth pattern are rare, and few urologists have encountered inverted urothelial carcinoma of the ureter. Case presentation An 82‐year‐old man was referred to our hospital for investigation of gross hematuria. Magnetic resonance imaging revealed nodules measuring 1–2 mm in diameter in the left upper ureter with slight reduction in signal intensity on diffusion‐weighted imaging. Ureteroscopy showed a pedunculated smooth tumor that had the appearance of an inverted papilloma rather than the papillary shape typical of urothelial carcinoma. The tumor was biopsied and histopathological examination revealed a noninvasive, low‐grade urothelial carcinoma with inverted multiple layers. Laparoscopic radical nephroureterectomy was subsequently performed, and a pedunculated tumor measuring 20 mm in diameter was found in the left upper ureter. The histopathological diagnosis was inverted papillary urothelial carcinoma, low‐grade, pTa, pN0. Conclusion This report provides the first clinical description of inverted papillary urothelial carcinoma of the ureter.

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