Open AccessTesticular metastasis from urothelial carcinoma of the bladder
Author(s) -
Fukagawa Eri,
Endo Fumiyasu,
Kyono Yoko,
Hashimoto Jun,
Hattori Kazunori
Publication year - 2022
Publication title -
iju case reports
Language(s) - English
Resource type - Journals
ISSN - 2577-171X
DOI - 10.1002/iju5.12398
Subject(s) - medicine , cystoscopy , metastasis , gemcitabine , urology , bladder cancer , differential diagnosis , pathological , urinary bladder , carcinoma , testicular cancer , chemotherapy , pathology , cancer , urinary system
Reports of urothelial carcinoma with testicular metastasis are limited and the etiology and prognosis remain unclear. We report a rare case of testicular metastasis derived from bladder urothelial carcinoma. Case presentation A 68‐year‐old man presented with gross hematuria and urinary frequency. Cystoscopy demonstrated an 8‐cm‐sized tumor in the bladder; transurethral resection and magnetic resonance imaging confirmed invasive urothelial carcinoma. Cystoprostatourethrectomy was performed, and the pathological diagnosis was high‐grade muscle‐invasive urothelial carcinoma. Three years later, the patient noticed a left scrotal mass. Left high orchiectomy was performed, and histopathologic examination of the surgical specimen revealed urothelial carcinoma, confirming testicular metastasis derived from bladder cancer. The patient received chemotherapy with gemcitabine and cisplatin and has survived for 7 years since the initial diagnosis without progression. Conclusion Although rare, secondary lesions should be considered for the differential diagnosis of testicular tumors in patients with a history of urothelial carcinoma.