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Drivers of advanced stage at breast cancer diagnosis in the multicountry A frican breast cancer – disparities in outcomes (ABC‐DO) study
Author(s) -
McKenzie Fiona,
Zietsman Annelle,
Galukande Moses,
Anele Angelica,
Adisa Charles,
Parham Groesbeck,
Pinder Leeya,
Cubasch Herbert,
Joffe Maureen,
Kidaaga Frederick,
Lukande Robert,
Offiah Awa U.,
Egejuru Ralph O.,
Shibemba Aaron,
Schuz Joachim,
Anderson Benjamin O.,
dos Santos Silva Isabel,
McCormack Valerie
Publication year - 2017
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.31187
Subject(s) - medicine , breast cancer , stage (stratigraphy) , odds ratio , cancer , confidence interval , demography , referral , cancer registry , logistic regression , gynecology , obstetrics , family medicine , paleontology , sociology , biology
Breast cancer (BC) survival rates in sub‐Saharan Africa (SSA) are low in part due to advanced stage at diagnosis. As one component of a study of the entire journey of SSA women with BC, we aimed to identify shared and setting‐specific drivers of advanced stage BC. Women newly diagnosed in the multicountry African Breast Cancer–Disparities in Outcomes (ABC‐DO) study completed a baseline interview and their stage information was extracted from medical records. Ordinal logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for advanced stage (I, II, III, IV) in relation to individual woman‐level, referral and biological factors. A total of 1795 women were included from Nigeria, Uganda, Zambia, and the multiracial populations of Namibia and South Africa, 1091 of whom (61%) were stage III/IV. Stage was lower in women with greater BC knowledge (OR 0.77 (95% CI: 0.70, 0.85) per point on a 6 point scale). More advanced stage was associated with being black (4.00 (2.79, 5.74)), having attended