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Optimized Batchwise and Continuous Microreactor Synthesis of a (Bathophenanthroline)ruthenium(II) Complex Carrying Different Ligands
Author(s) -
Kramer Rolf A.,
Rumi Luigi,
Bannwarth Willi
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200800353
Subject(s) - chemistry , microreactor , ruthenium , combinatorial chemistry , catalysis , organic chemistry
AbstractBy changing the Ru‐source, the reaction conditions, and the workup/purification procedure, the batchwise synthesis of a mixed [Ru II (bathophenanthroline)] complex, i.e. , of 4b , could substantially be improved (bathophenanthroline=4,7‐diphenyl‐1,10‐phenanthroline). In addition, we were able to adapt both steps of the synthesis to a microreactor system leading to the desired Ru‐complex in a continuous preparation in very high yields. The latter approach is especially suited for an envisaged scale‐up.