Open AccessHigh‐Fat Diet Modulates Hepatic Amyloid β and Cerebrosterol Metabolism in the Triple Transgenic Mouse Model of Alzheimer’s Disease
Author(s) -
Bosoi Cristina R.,
Vandal Milène,
Tournissac Marine,
Leclerc Ma,
Fanet Hortense,
Mitchell Patricia L.,
Verreault Mélanie,
Trottier Jocelyn,
Virgili Jessica,
Tremblay Cynthia,
Lippman H. Robert,
Bajaj Jasmohan S.,
Barbier Olivier,
Marette André,
Calon Frédéric
Publication year - 2021
Publication title -
hepatology communications
Language(s) - English
Resource type - Journals
ISSN - 2471-254X
DOI - 10.1002/hep4.1609
Subject(s) - medicine , endocrinology , insulin degrading enzyme , lipogenesis , steatosis , fatty liver , genetically modified mouse , insulin resistance , lipid metabolism , insulin , biology , transgene , disease , biochemistry , gene
Long‐term high‐fat diet–induced changes in liver function impact peripheral AD features and should be considered during development of biomarkers or therapeutic targets.