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IFN‐I signaling exacerbate liver pathology and contribute to sepsis following fatal  Ehrlichia  infection by promoting  Ehrlichia  replication and mediating detrimental inflammasome activation.

hepatology communications

Interferon Type I Regulates Inflammasome Activation and High Mobility Group Box 1 Translocation in Hepatocytes During  Ehrlichia ‐Induced Acute Liver Injury