Open AccessBrain gray matter structures associated with trait impulsivity: A systematic review and voxel‐based meta‐analysis
Author(s) -
Pan Nanfang,
Wang Song,
Zhao Yajun,
Lai Han,
Qin Kun,
Li Jingguang,
Biswal Bharat B.,
Sweeney John A.,
Gong Qiyong
Publication year - 2021
Publication title -
human brain mapping
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.005
H-Index - 191
eISSN - 1097-0193
pISSN - 1065-9471
DOI - 10.1002/hbm.25361
Subject(s) - impulsivity , trait , psychology , neuroimaging , voxel based morphometry , meta analysis , brain morphometry , voxel , neuroscience , clinical psychology , white matter , medicine , magnetic resonance imaging , pathology , computer science , radiology , programming language
Trait impulsivity is a multifaceted personality characteristic that contributes to maladaptive life outcomes. Although a growing body of neuroimaging studies have investigated the structural correlates of trait impulsivity, the findings remain highly inconsistent and heterogeneous. Herein, we performed a systematic review to depict an integrated delineation of gray matter (GM) substrates of trait impulsivity and a meta‐analysis to examine concurrence across previous whole‐brain voxel‐based morphometry studies. The systematic review summarized the diverse findings in GM morphometry in the past literature, and the quantitative meta‐analysis revealed impulsivity‐related volumetric GM alterations in prefrontal, temporal, and parietal cortices. In addition, we identified the modulatory effects of age and gender in impulsivity‐GM volume associations. The present study advances understanding of brain GM morphometry features underlying trait impulsivity. The findings may have practical implications in the clinical diagnosis of and intervention for impulsivity‐related disorders.