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Summary  The International League Against Epilepsy/American Epilepsy Society ( ILAE / AES ) Joint Translational Task Force created the  TASK 3 working groups to create  common data elements ( CDE s)  for various aspects of preclinical epilepsy research studies, which could help improve standardization of experimental designs . This article concerns the parameters that can be measured to assess the physiologic condition of the animals that are used to study rodent models of epilepsy. Here we discuss  CDE s for physiologic parameters measured in adult rats and mice such as general health status, temperature, cardiac and respiratory function, and blood constituents. We provide detailed  CDE  tables and case report forms ( CRF s), and with this companion manuscript we discuss the monitoring of different aspects of physiology of the animals. The  CDE s,  CRF s, and companion paper are available to all researchers, and their use will benefit the harmonization and comparability of translational preclinical epilepsy research. The ultimate hope is to facilitate the development of biomarkers and new treatments for epilepsy.

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A companion to the preclinical common data elements for physiologic data in rodent epilepsy models. A report of the  TASK 3 Physiology Working Group of the  ILAE / AES  Joint Translational Task Force