English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

The kinetic resolution of α‐substituted aminopentenes via intramolecular hydroamination was investigated using various 3,3′‐silyl‐substituted binaphtholate yttrium catalysts. High efficiencies in the kinetic resolution were observed for methyl‐, benzyl‐, and phenyl‐substituted substrates utilizing the cyclohexyldiphenylsilyl‐substituted catalyst  2c  with resolution factors reaching as high as 90(5) for hex‐5‐en‐2‐amine ( 3a ). Kinetic analysis of the enantioenriched substrates with the matching and mismatching catalyst revealed that the efficiency of catalyst  2c  benefits significantly from a favorable Curtin–Hammett pre‐equilibrium and by a large  k fast /k slow   ratio. Other binaphtholate catalysts were less efficient due to a less favorable Curtin–Hammett pre‐equilibrium, which often favored the mismatching substrate‐catalyst combination. Cyclization of the matched substrate proceeds generally with large  trans ‐selectivity, whereas the  trans/cis ‐ratio for mismatched substrates is significantly diminished, favoring the  cis ‐cyclization product isomer in some instances.

european journal of organic chemistry

Rare‐Earth‐Metal‐Catalyzed Kinetic Resolution of Chiral Aminoalkenes via Hydroamination: The Effect of the Silyl Substituent of the Binaphtholate Ligand on Resolution Efficiency