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BEt 3 ‐Initiated Thiol–Ene Click Reactions as a Versatile Tool To Modify Sensitive Substrates
Author(s) -
Gorges Jan,
Kazmaier Uli
Publication year - 2015
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201500915
Subject(s) - thiol , chemistry , ene reaction , click chemistry , stoichiometry , combinatorial chemistry , polymer chemistry , organic chemistry
BEt 3 ‐initiated thiol–ene click reactions are an interesting alternative to the generally used thermal or photochemical thiol additions. The reactions proceed under very mild conditions, and require only 10 mol‐% of BEt 3 , and an almost stoichiometric amount of thiol. In this regard, this method is an attractive alternative to the other protocols, which often use the thiol component in a large excess.
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