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Reaction‐Based Europium Complex for Specific Detection of Cysteine Over Homocysteine and Glutathione with Variable‐Temperature Kinetic Studies
Author(s) -
Yip YukWang,
Yan Zhiyuan,
Law GaLai,
Wong WingTak
Publication year - 2019
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/ejic.201801315
Subject(s) - chemistry , cysteine , glutathione , europium , quenching (fluorescence) , homocysteine , thiol , fluorescence , biochemistry , organic chemistry , enzyme , ion , physics , quantum mechanics
A water‐soluble europium(III)‐based probe, EuL , has been designed and synthesized for selective recognition of cysteine (Cys) over other structurally similar thiols and amino derivatives due to formation of a more stable and preferable seven‐membered ring. Addition of Cys shows a significant response with quenching of over 90 % of the initial signal (Hcys: 10.5 %, GSH: 3.6 % respectively). A good linear correlation between the emission intensities and concentrations of Cys has been established.