Open AccessWhat's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
Author(s) -
Amelotti Nicola,
Mapelli Massimo,
Guglielmo Marco,
Pires Maria Inês Fiuza Branco,
Campodonico Jeness,
Majocchi Benedetta,
Ribatti Valentina,
Vettor Giulia,
Baggiano Andrea,
Catto Valentina,
Basso Cristina,
Pontone Gianluca,
Agostoni Piergiuseppe
Publication year - 2023
Publication title -
esc heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.787
H-Index - 25
ISSN - 2055-5822
DOI - 10.1002/ehf2.14172
Subject(s) - medicine , myocarditis , eosinophilia , heart failure , cardiology , eosinophilic , hypereosinophilic syndrome , pathology
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started.