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Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure –A clinical practice Guideline Level 3
Author(s) -
Assmann Alexander,
Beckmann Andreas,
Schmid Christof,
Werdan Karl,
Michels Guido,
Miera Oliver,
Schmidt Florian,
Klotz Stefan,
Starck Christoph,
Pilarczyk Kevin,
Rastan Ardawan,
Burckhardt Marion,
Nothacker Monika,
Muellenbach Ralf,
Zausig York,
Haake Nils,
Groesdonk Heinrich,
Ferrari Markus,
Buerke Michael,
Hennersdorf Marcus,
Rosenberg Mark,
Schaible Thomas,
Köditz Harald,
Kluge Stefan,
Janssens Uwe,
Lubnow Matthias,
Flemmer Andreas,
HerberJonat Susanne,
Wessel Lucas,
Buchwald Dirk,
Maier Sven,
Krüger Lars,
Fründ Andreas,
Jaksties Rolf,
Fischer Stefan,
Wiebe Karsten,
Hartog Christiane S.,
Dzemali Omer,
Zimpfer Daniel,
RuttmannUlmer Elfriede,
Schlensak Christian,
Kelm Malte,
Ensminger Stephan,
Boeken Udo
Publication year - 2022
Publication title -
esc heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.787
H-Index - 25
ISSN - 2055-5822
DOI - 10.1002/ehf2.13718
Subject(s) - extracorporeal membrane oxygenation , medicine , guideline , intensive care medicine , life support , extracorporeal circulation , extracorporeal , surgery , pathology
Aims Worldwide applications of extracorporeal circulation for mechanical support in cardiac and circulatory failure, which are referred to as extracorporeal life support (ECLS) or veno‐arterial extracorporeal membrane oxygenation (va‐ECMO), have dramatically increased over the past decade. In spite of the expanding use and the immense medical as well as socio‐economic impact of this therapeutic approach, there has been a lack of interdisciplinary recommendations considering the best available evidence for ECLS treatment. Methods and Results In a multiprofessional, interdisciplinary scientific effort of all scientific societies involved in the treatment of patients with acute cardiac and circulatory failure, the first evidence‐ and expert consensus‐based guideline (level S3) on ECLS/ECMO therapy was developed in a structured approach under regulations of the AWMF (Association of the Scientific Medical Societies in Germany) and under use of GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria. This article presents all recommendations created by the expert panel, addressing a multitude of aspects for ECLS initiation, continuation, weaning and aftercare as well as structural and personnel requirements. Conclusions This first evidence‐ and expert consensus‐based guideline (level S3) on ECLS/ECMO therapy should be used to apply the best available care nationwide. Beyond clinical practice advice, remaining important research aspects for future scientific efforts are formulated.

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