Open AccessIntractable coronary fibromuscular dysplasia leading to end‐stage heart failure and fatal heart transplantation
Author(s) -
Cattaneo Magdalena Maria,
Moccetti Marco,
Cattaneo Mattia,
Sürder Daniel,
Suter Thomas,
Martinelli Michele,
Roost Eva,
Schmidli Jürg,
Banz Yara,
Schneiders Carmen,
Pedrazzini Giovanni,
Corti Roberto,
Räber Lorenz,
Crea Filippo,
Mohacsi Paul,
Gallino Augusto
Publication year - 2020
Publication title -
esc heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.787
H-Index - 25
ISSN - 2055-5822
DOI - 10.1002/ehf2.12626
Subject(s) - medicine , fibromuscular dysplasia , cardiology , restenosis , heart failure , percutaneous coronary intervention , intimal hyperplasia , heart transplantation , transplantation , autopsy , dissection (medical) , dysplasia , surgery , myocardial infarction , stent , renal artery , smooth muscle , kidney
Coronary fibromuscular dysplasia is uncommon, and even rarer its unstable and recurrent course. We present the unique case of a 52‐year‐old woman who underwent in total 12 coronary angiographies and three percutaneous coronary intervention within 24 months because of repetitive acute coronary syndromes due to refractory spasm, dissection, restenosis all leading to end‐stage heart failure, and heart transplantation. The patient died 12 days after the heart transplantation complicated by intraoperative acute thrombotic occlusion of left anterior descending artery of the graft despite normal pretransplant coronary angiography. Autopsy of the recipient heart confirmed coronary fibromuscular dysplasia with massive intimal hyperplasia and restenosis.