Open AccessFrailty may be a risk marker for adverse outcome in patients with congestive heart failure
Author(s) -
Yamada Sumio,
Kamiya Kuniyasu,
Kono Yuji
Publication year - 2015
Publication title -
esc heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.787
H-Index - 25
ISSN - 2055-5822
DOI - 10.1002/ehf2.12052
Subject(s) - medicine , heart failure , risk stratification , grip strength , cardiology , adverse effect , cohort , cohort study , intensive care medicine , physical therapy
Abstract Aims To examine the availability of frailty concept with objective criteria for risk stratification in patients with congestive heart failure (CHF). Methods and results Study design was secondary analysis of our CHF cohort. We selected 181 patients who completed clinical assessments and were successfully followed 2‐year post discharge. To set frailty criteria, grip strength <26 kg in men and <17 kg in women (weakness) and performance measure for activities of daily living‐8 ≧21 points (exhaustion) were defined for predicting 6 min walking distance <300 m (slowness) by the receiver‐operating characteristics. During 2 years of follow up, subjects who met all the criteria had a 4 times greater risk of cardiac event compared with those with no frailty criteria. Conclusion The findings of present study suggest that frailty criteria may serve as a new clinical marker for management of patients with CHF.